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Elidel Cream is the strongest anti-inflammatory remedy for the external use. It is used as an anti-inflammatory remedy for the severe forms of dermatitis. The active component of the drug is pimecrolimus. It is a selective inhibitor of the synthesis and release of inflammatory mediators during the allergic reactions and different irritants. It inhibits the secondary immune response in the isolated cells of the skin, and so it delays the development of the reaction.

Unlike hormonal anti-inflammatory remedies pimecrolimus affects the growth of keratinocyte endothelial cells. It provides a direct action to the cells of the immune system and does not cause the dysfunctions of the cells and metabolisms in the body of the patient. The uniqueness of the action mechanism of pimecrolimus consists in the combination of the selective anti-inflammatory action to the skin with slight effect to the systemic immune response.

During the local use on the experimental models of the allergic contact dermatitis Elidel Cream is comparable with highly active corticosteroids. It inhibits the inflammatory reaction in response to the effect of the skin irritants without causing changes in the consistence and atrophy of the skin. According to the rates of the efficiency Elidel Cream is safer than corticosteroids but is not less effective. Therefore, this drug is recommended most patients including in pediatric practice.

Direction for the use:

Elidel Cream is prescribed for the treatment of the atopic dermatitis (eczema) both within a long period and short-term preventive therapy. Also, the use of the drug is possible during other types of dermatitis but only after the examination in the health care provider.

Elidel Common Use

• Elidel Cream may be equally prescribed adults and children older 3 months. In most cases the identical drugs are contraindicated in the pediatric practice.
• It is recommended to use the cream during the first signs of the disease in order to prevent a sudden worsening of the symptoms of the allergic reactions.
• The cream is applied thin layer to the affected area of the skin 2 times per day, and is carefully rubbed until the complete absorption of the cream into the skin.
• Elidel Cream may be applied to any parts of the skin (face, neck) except area around eyes, mucous membrane of the mouth or nasal cavity.
• It is necessary to use the drug up to the complete disappearance of the symptoms. The prolong use of the cream does not cause the physical addiction in the patients and reduction of the efficiency.
• In case of the absence of the significant reduction of the symptoms in 6 weeks of the drug use it is necessary to see a doctor and have medical examination to specify the diagnosis.

Contraindications

• Elidel Cream is contraindicated children under 3 months, in case of the individual intolerance pimecrolimus or any components of the drug.
• The application of the drug to the areas of the skin affected by the bacterial, viral or fungal infections is contraindicated.
• Pregnant women should be careful while taking Elidel Cream. The fact that the active component has minimal level of the absorption allows using the drug during pregnancy but under the supervision of the doctor.
• Feeding women can also use this remedy but they should not apply the cream to the area of breasts in order to eliminate any risk of the penetration of pimecrolimus into the milk.
• In the course of the studies the effect of Elidel Cream to the patients with weak immunity has not been fully studied. Therefore, it is not recommended this category of patients to use the drug.

Possible Side effects

The use of Elidel Cream may cause slight transient reactions in the area of the application such as feeling of burning in the area of the cream application, irritation, itching and redness of the skin, and folliculitis.

In most cases the appearance of the side effects they passed mildly and did not require the medical intervention. The side effects pass without complications within several days.

 

International name - Pimecrolimus

Elidel Cream 10g/1%

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