Elidel Cream is the strongest anti-inflammatory remedy for the external use. It is used as an anti-inflammatory remedy for the severe forms of dermatitis. The active component of the drug is pimecrolimus. It is a selective inhibitor of the synthesis and release of inflammatory mediators during the allergic reactions and different irritants. It inhibits the secondary immune response in the isolated cells of the skin, and so it delays the development of the reaction.
Unlike hormonal anti-inflammatory remedies pimecrolimus affects the growth of keratinocyte endothelial cells. It provides a direct action to the cells of the immune system and does not cause the dysfunctions of the cells and metabolisms in the body of the patient. The uniqueness of the action mechanism of pimecrolimus consists in the combination of the selective anti-inflammatory action to the skin with slight effect to the systemic immune response.
During the local use on the experimental models of the allergic contact dermatitis Elidel Cream is comparable with highly active corticosteroids. It inhibits the inflammatory reaction in response to the effect of the skin irritants without causing changes in the consistence and atrophy of the skin. According to the rates of the efficiency Elidel Cream is safer than corticosteroids but is not less effective. Therefore, this drug is recommended most patients including in pediatric practice.
Elidel Cream is prescribed for the treatment of the atopic dermatitis (eczema) both within a long period and short-term preventive therapy. Also, the use of the drug is possible during other types of dermatitis but only after the examination in the health care provider.
The use of Elidel Cream may cause slight transient reactions in the area of the application such as feeling of burning in the area of the cream application, irritation, itching and redness of the skin, and folliculitis.
In most cases the appearance of the side effects they passed mildly and did not require the medical intervention. The side effects pass without complications within several days.
International name - Pimecrolimus
Elidel Cream 10g/1%