Metronidazole Gel is an antimicrobial medical product which is successfully used in dermatology and venerology. This drug provides a bactericidal and bacteriostatic action. Depending on the concentration of the active component Metronidazole in the gel this drug shows the most optimal action as to different bacteria and causative agents of the infectious diseases.
Metronidazole Gel also has an antioxidant activity. It is established that it significantly reduces the production of neutrophils of the active oxygen and hydrogen which are the potential oxidants which are able to cause the affection of the tissues in the area of the inflammation. In the course of the drug use it was indicated that it provides the strongest antiprotozoal action. The mechanism of the action consists in the biochemical recovery of 5-nitro group – molecules which are spread in our cells. 5-nitro group interaction with DNA cells of the morbific microorganisms blocking their access to protein. Breaking the protein metabolisms Metronidazole stops the growth and development of bacteria and gradually leads to their death.
This drug is effective as to wide range of the causative agents: Trichomonas vaginalis, Gardnerella vaginalis, Lambliaspp, Bacteroides vulgatus, Peptococcusspp, and many other aerobic microorganisms, and therefore this drug is often prescribed with peroral antibiotics in order to increase the efficiency of the treatment.
In some cases the gel may be used for the treatment of acne rosacea and acne vulgaris.
Metronidazole Gel may cause local reactions: hyperemia, dryness of the skin, feeling of the burning, and irritation of the skin. Using the gel in the area around the eyes lacrimation is possible. These side reactions do not require the medical intervention and pass.
In most cases, following all recommendations to the use this drug does not cause the side effects and are well tolerated.
International name - metronidazole
Metronidazole Gel 20g 5%
Metrogyl DG 20g dental gel (+ Chlorhexidine Gluconate (0.25 % w/w/1 g.) Metronidazole (1 % w/w)
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