Lotrisone cream is a combined drug for the external use. It contains two active components – Clotrimazole and Betamethasone. This drug is used for the treatment of the different skin diseases which are caused by the fungal infections.
It is one of the most effective remedies for the treatment of the skin diseases. The pharmacological efficiency is explained by the action of two active components which supplement the pharmacological properties of each other.
Clotrimazole is an antifungal remedy with broad-spectrum action. It is active as to dermatophytes and yeast-like fungi. Moreover, it is active as to trichomonad, staphylococci, and streptococci. Its mechanism of the action consists in the penetration to DNA of the fungi cell and destruction of their intracellular compounds. Blocking the development and the growth of fungi on the molecular level this drug quickly reduces the disease symptoms and prevents the relapses.
Betamethasone is glucocorticosteroid, provides the anti-inflammatory, antipruritic and anti-allergic action. It influences on all phases of the inflammation. The anti-allergic action develops as a result of the reduction of the synthesis and secretion of the allergy mediators.
The medical interaction of Clotrimazole and Betamethasone allows to increase the efficiency of the treatment of the skin diseases both inflectional and allergic character. Lotrisone Cream is one of the most used remedies for the treatment of the skin diseases which differ by a good tolerance and absence of the severe side effects.
In case of the resistant bacterial or fungal microflora it is necessary to cancel the drug and prescribe the attendant therapy.
The most common local side reaction during the use of Lotrisone cream are itching, burning, irritation, dry skin, folliculitis, and high sweating.
Most side effects are temporary and pass in several days after the beginning of the treatment.
Using high doses of the cream to big parts of the skin the development of such side effects as increased arterial pressure, edemas, disorder of the organs of the gastrointestinal tract, and allergic reactions are possible. If these symptoms appear, the intervention of the medical doctor is needed.
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International name - betamethasone/clotrimazole